At what point of ±% resting heart rate would one define as significant increase/decrease in heart rate. For example, if one had a resting heart rate of 60 bpm, would an increase to 75 BPM be considered a significant elevation, or would a greater increase have to take place in order to be considered significant?
I think as long as within the normal range its "not significant", so many factors affecting my HR that for me at night from 50 /min going to 65 would be significant, for someone with a normal HR of 70 going 90 during the day I guess its not significant, I dont think there is much information about this, but as a clinician I believe significant should cause something like a sign or symptom that turn the light of "significance"
Thanks for the answer. In sport physiology, there is the 60% HF max, and 80% HF max, meaning that at those points, there is a physiological effect, and thereby significant. What happens at 10,20,30,40,50% HF max, is maybe a no-mans land. Of course a clinical sign (i.e Shock index >1.0) would be significant. I guess one just has to interpret the situation based on activity, and resting heart rate. However, depneding on the situation, would a 20% increase from resting heart rate be considered physiologically significant? The stroke volume would decrease, sympathetic tone has been increased, and maybe the metabolism as well. Perhaps when someone is suddenly exposed to bad news or something similar.
Thanks for the answer.To determine the importance of increasing the heart rate, you must first determine the conditions of its registration:
1. Sitting, standing, lying down, etc.
2. Standardization of measurement (a method or instrument that registers the heart rate).
3. Standardize the influence of the studied factors (capacity of exercise, medication dose, etc.).
Further, all of the statistics.
Dear Michael. In our research group we have designed something called the fitness calculator (http://www.ntnu.edu/cerg/vo2max). Here we show, based on results from ~6000 individuals testing their VO2max, that resting heart rate is closely associated with VO2max, which again is an important CVD risk factor. If you test different conditions, and then switching between a resting heart rate of 60 versus 75, you can see a large difference in estimated VO2max and biological age. Then it might be easier to decide whether your change in resting heart rate is of importance.
Significant factors in heart rate changes if a system can be said to pay attention to various factors that Tghyrat Asrdarnd (color and Vsbany the rest of sports medicine etc) and its effects on
CNS AND ANS
And stimulate the Sympathetic and Parasympatyk so it should be a discontinuous function, so the heart rate is influenced by various elements Tghyr and the model can be measured
The foregoing answers have all appeared to assum healthy people. i.e. normal exercise physiology. You don't state the target population in your query.
Clinicians use an arbitrary normal range for resting heart rate of 60-100bpm. I presume a statistician would say that anything within 2 standard deviations of a person's mean heart rate would be normal for them (in any given circumstance). Obviously exercise - or anything else that affects prevailing autonomic activity, for example anxiety - needs to be taken into account.
There are some data around examining the effects of age and other factors on heart rate variability, for example: Heart rate variability in an ageing population and its association with lifestyle and cardiovascular risk factors: results of the SAPALDIA study http://europace.oxfordjournals.org/content/8/7/521
Apart from pathology (e.g. autonomic neuropathy, sinoatrial node disease, etc), people on a variety of medications will have different heart rate responses (e.g. negatively chronotropic drugs like digoxin and beta-blockers slowing the maximal heart rate, and drugs with anticholinergic activity* raising the minimum rate).
For all these reasons, it is impossible to give a simple, clear, universal answer to your query. It is context-specific, and also person-specific.
*http://www.ephor.nl/media/1076/anticholinergic-drugs.pdf
The foregoing answers have all appeared to assum healthy people. i.e. normal exercise physiology. You don't state the target population in your query.
Clinicians use an arbitrary normal range for resting heart rate of 60-100bpm. I presume a statistician would say that anything within 2 standard deviations of a person's mean heart rate would be normal (in any given circumstance). Obviously exercise - or anything else that affects prevailing autonomic activity, for example anxiety - needs to be taken into account.
There are some data around examining the effects of age and other factors on heart rate variability, for example: Heart rate variability in an ageing population and its association with lifestyle and cardiovascular risk factors: results of the SAPALDIA study http://europace.oxfordjournals.org/content/8/7/521
Apart from pathology (e.g. autonomic neuropathy, sinoatrial node disease, etc), people on a variety of medications will have different heart rate responses (e.g. negatively chronotropic drugs like digoxin and beta-blockers slowing the maximal heart rate, and drugs with anticholinergic activity* raising the minimum rate).
For all these reasons, it is impossible to give a simple, clear, universal answer to your query. It is context-specific, and also person-specific.
*http://www.ephor.nl/media/1076/anticholinergic-drugs.pdf
Thank you all very much for giving some thought to the original question posed concerning significant changes in baseline HR.
Yes, the group being examined is from a cohort of healthy individuals, i.e control group.
If I may add an additional question to the inquiry;
Would an 30-45% HRmax have any metabolic effects, or physiological significance for a healthy human, without CV risk factors, or any background pathophysiology?
There will be a direct association (probably, for this lower part of the range, fairly linear) between any additional increase in heart rate and the resulting metabolic (e.g. CO2 production) & physiological (e.g BP, RR, peripheral resistance, etc) effects.
How 'significant' these changes are will depend critically on what you are planning to do in the intervention arm. Impossible to advise without further detail!
Hi Michael. I'm also trying to find an answer to your question. Since a smallest worthwhile (SwC) or minimal clinical important difference (MCID) has not been established it's unlikely that anyone can be more right than wrong. For now, I'm thinking that you've got to take into consideration (a) how precise you want to be (95% confidence), (b) how reliable is the device in question (i.e. test-retest), and the number of samples taken to determine mean resting heart rate (1 or 100)? All of the above assumes the testing conditions are ~identical T1-T2... T3.