Cross resistance among pathogens is becoming a serious treat to the treatment of infectious diseases.
You should use antimicrobials after antimicrobial susceptibility test and also correct using time and dose. Also first of all, when you use disinfectant regarding of their users practice, almost all pathogenic microbiota could be eliminated. Especially, if you don't want to antimicrobial resistance, you must avoid using antibiotics.
It is imperative to first identify the factors responsible for cross resistance. If you don't mind, you can read through the following two articles which broad pertinent exposition:
1. Article Antibiotic Resistant Superbugs: Assessment of the Interrelat...
2. Article Stenotrophomonas maltophilia as an Emerging Ubiquitous Patho...
The overuse and misuse of antibiotics are what prompted the increase in this phenomenon and for the various pathogens. One of the most important of these uses is the use of antibiotics as growth stimulants for animals and to improve the health condition during the breeding period. This makes breeders use many antibiotics, and unfortunately, sometimes they do not adhere to the permissible limit of additives, and if we know that approximately 90% of these drugs are not absorbed by the intestine, but rather will be excreted with the urine or with feces, and pollute the environment, bedding, and animal homes with their residues, so we will realize the role it plays in creating selective pressure on the bacterial species present in the environment, whether these types are pathogenic or environmental bacteria, so we will have strains resistant to antibiotics and mostly appear by commensals bacteria because such bacteria possess many drug resistance genes, but due to the genetic transfer between bacterial species, there is a possibility of transmission of resistance to pathogens, which poses a real threat to public health, especially if this resistance to life-saving antibiotics. Therefore, if we want to limit this phenomenon, strict measures and laws must be taken that prohibit the use of antibiotics as growth stimulants, and if they are used, it must be according to specific constitutions and laws that do not allow them to be added more than the permissible limit, and it is also preferable to replace them with organic salts ... Also, the letter should be treated to get rid of the residual effects that may pose a threat to the environment. In fact, many studies indicate the high percentage of the Multidrug resistance index, which indicates that breeders and farmers do not abide by the laws during breeding, and these studies also indicate that the high pollution rates of agricultural crops with resistant pathogens may be caused by the use of organic fertilizer contaminated with residues.
Kindly check the following RG link for the article entitled What are the effective solutions to control the dissemination of antibiotic resistance in the environment? A systematic review protocol
Article What are the effective solutions to control the disseminatio...
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