How can we identify the tryptophan oxidation site in mAbs?

07 March 2017 1 6K Report

I have tried with AAPH as a oxidizing agent for forceful oxidation of tryptophan but not able to get the desired oxidized peaks in LC. Can someone suggest the best way to do it?

Rekha Jadon

Thanks Clark....I will try..but I am looking for stability studies for mAbs?

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