How can we analyze lcms data with mz and rt time. Is it necessary that RT should match with the other research publications that has same mz value?

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Yannis Karamanos

For a given compoun, in a given LC column, we will obtain a specific RT and a specific m/z ratio. When you compare with data of other publications it is very likely to observe different RT. But, with your LC column, under your chromatographic conditions you will always observe a specific RT and the corresponding m/z ratio.

Md Humayun Kabir

If m/z same then no need to care for RT , because in different condition RT can be changed.