Check cross references

Where it it. Is?

Hoq

To synthesize 2,2'-bipyridine-5,5'-dicarbaldehyde, see

---Jana Hodaová; Miloš Budšínský, Organic Letters. 2007, 9, 5641-5643

What is 5,5'-dimethylbromo-2,2'-bipyridine? Do you mean 5,5'-bis(bromomethyl)-2,2'-bipyridine?

Good luck

Or do you mean 5,5'-bis(dibromomethyl)-2,2'-bipyridine

Please, clarify the correct name for your starting material if you still need help

Good luck

There is a simple way to make benzyl bromides to corresponding aldehydes. To a solution of 2 mmol bromide in 2.5 ml DMSO was added 2 mmol of AgNO3 and 0.1 g of NaHCO3, the resulting mixture is stirred vigorously under nitrogen for 1 h then 0.25 ml TEA is added and stirred for an additional 15 mins, then poured in to water and extracted with suitable solvent.

ref: Ghera, E.; Plemenitas, A.; Ben-David, Y. Synthesis 1984, 505.

Do the Sommelet Reaction i.e. treat your bromomethylated pyridine with hexamethylene tetra-amine followed by acidic hydrolysis.

follow the procedure, http://pubs.acs.org/doi/abs/10.1021/jo500330r

HI Adel AMer , I meant 5,5'-bis(dibromomethyl)-2,2'-bipyridine

Senthilmurugan Annamalai .. Thanks you very much.. But Can you give me the link thate related literature ?? Thanks again

HI Dhirendra Kumar.. Thanks .. I dont have access into Jacs,.. I will check it .. I appreciate your help

Hi Adel AMer . If you have any procedure to 5,5'-dicarbaldehyde-2,2'-bipyridine from 5,5'-bis(dibromomethyl)-2,2'-bipyridine, Please help me out. Thanks

http://www.chemie.uni-duesseldorf.de/Faecher/Anorganische_Chemie/AC1/Janiak/Pdf/80.pdf

Here is the article

Hi Amir > WOuld you help me to download full paper of this link..https://scifinder.cas.org/scifinder/view/scifinder/scifinderExplore.jsf??? If I click here, it directs to different site .... Literature name is Symmetrical and unsymmetrical derivatives of 5,​5'-​dimethyl-​2,​2'-​bipyridine

By: Al-Sayah, M. H.; Salameh, A. S... PLease Help me. Thanks

Hi Md Hoq

Find the attached paper and supporting have the procedure in details, good luck

Supporting info

Mohamed thanks for your link.but this link is different..

Hoq,

You wrote

The procedure will be similar to the described one by A. E. Moormann et al, Synthetic Communications, 17(14),1695-1699 (1987)

To a solution of your5,5'-bis(dibromomethyl)-2,2'-bipyridine (50 mmol) in ethanol (250 ml) is added conc. NH4OH (~30 ml) at 4° C. The reaction mixture is stirred 15 minutes at 4° C. then stirred at room temperature for 3 hours. Reaction mixture is concentrated under reduced pressure. To the concentrated residue is added conc. HCl (150 ml) and mixture is refluxed for 3 hours. The reaction mixture is cooled to room temperature and concentrated. To the concentrated residue is added water (25 ml) then added saturated K2CO3 to neutralize the solution. The solu­tion is extracted with methylenechloride (3x150 ml). Combined organic solution is washed with water (3x150 ml), brine (1x200 ml), dried over Na2SO4. The concentrated residue is suspended in ether, filtered and washed with ether.

I hope this will work

Good luck

Amer thank you very much.you alway helped me. Please if possible give me download link