How can I separate osmium tetroxide and NMO in dihydroxylation of alkenes?

22 May 2015 1 9K Report

I performed dihydroxylation of alkenes in presence of catalyst osmium tetroxide and co-oxidant NMO. Final product is diol. How can we separate osmium tetroxide and co-oxidant NMO from final product diol?

Olívio Fernandes Galão

Di asymmetric Sharpless dihydroxylation is the chemical reaction of an alkene with osmium tetroxide.Is common practice to carry out this reaction by using a catalytic amount of osmium tetroxide, which is regenerated after the reaction with potassium ferricyanide or N-methylmorpholine oxide , this dramatically reduces the amount of highly toxic osmium tetroxide and very costly necessary

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