I am preparing approx 450nm particles, but they have a high dispersity in size (15%). How can i use a centrifuge to remove larger particles (approx 600nm) and get the dispersity down to
It would seem you need a frit of 600nm at the bottom of your centrifugal tubes. There is a vendor, SilcoTek that makes such frits.
Dear Joe Mcgrath thank you for your interesting technical question. In this context please have a look at the following potentially useful presentation:
Analytical Ultracentrifugation Analytical Ultracentrifugation of Nanoparticles
http://www.nanoparticles.org/pdf/37-Coelfen.pdf
Also please see:
Measuring the size and density of nanoparticles by centrifugal sedimentation and flotation
https://pubs.rsc.org/en/content/articlehtml/2018/ay/c8ay00237a
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