Genetics Statistics data analysis
Suppose I have data for single SNP: Case- CC- 54, CG-23, GG-13 and for control: CC- 75, CG-10, GG- 5. How can I perform the Bonferroni correction of p-values generated with the odds ratio for the different genetic models?
CG: OR =3.19, P=0.006
GG: OR=3.61, P=0.021
CG+GG: OR=3.33, P=0.0007
G allele: OR=2.99, P=0.0002
If I have another SNP, where CC- 55, CT- 24, TT-11 for cases and CC-73, CT-13, TT-4 for controls
CT: OR =2.45, P=0.021
TT: OR=3.65, P=0.034
CT+TT: OR=2.73, P=0.004
T allele: OR=2.60, P=0.0009
How can I perform the Bonferroni correction of p-values generated with the odds ratio for the different genetic models in case both the SNPs?