Actually I'm doing the reaction of bis alkyne with 2 azidopyridine but in this reaction yield is less , can anyone suggest to increase the yield of reaction bcoz in reaction reduction also occurring!
14 December 2020 5,935 3 View
Dear researcher, kindly suggest me a good standard organisational survey to measure organisational effectiveness. I went through a survey developed by Taylor and Bower (1972) but could not find...
09 June 2020 6,923 1 View
Dear RG community, I am modeling the thermal abuse behavior of Li-ion cylindrical cell using COMSOL 5.4. Two models are coupled, i.e. 1D electrochemical model (to evaluate the heat generation)...
14 April 2020 8,606 6 View
I have modeled a protein, performed MD simulation and Docking studies. What are the other/additional computational study that can be performed further in order to target a high impact journal.
16 April 2019 168 6 View
K_UL and Kcel are matrices. M1=4; M2=4; nK = size(K_UL,2); Us=zeros(ndof,nK); for x=-M1:1:0 for y=-M2:1:M2-1 fx=1i*pi*x/M1;...
05 November 2018 174 3 View
I want to learn and understand the spectrograms associated with emotional speech. I'm looking for the sample code for this purpose. Something like this: https://github.com/AzamRabiee/Emotional-TTS...
19 October 2018 4,973 1 View
Hi, I've just started my PhD in Computer Science. My area of interest is Emotion AI (Affective Computing), which aims to understand emotions in Image, Video, Speech, Body-language and Brain-wave...
23 September 2018 4,782 5 View
Sample size estimation for cross sectional studies- i am trying to explore where exactly we use an absolute precision and where we use relative precision.
05 September 2018 6,361 2 View
Hello all, I am doing a project on resource allocation in LTE device to device communication. Can anyone suggest a Q learning based matlab code for that? Thanks in advance Br Puneet Sharma
14 August 2018 3,716 3 View
I want to buy cheap labeled RNA oligos. i inquired in Sigma but it was very costly. Are there any company in India which are supplying these oligos for a cheaper price? 5'-(TAMRA)UUUUUU-3'?
04 January 2017 8,343 1 View
I am working on identification of a small peptide in brain tissue. We have modified the peptide with alkyne modifications for azide-based clicking. For Click reaction we have used 50 uM CuSO4,...
23 September 2019 8,052 3 View
08 September 2019 8,510 2 View
FT-IR analysis of N-acetyl-D-glucosamine (NAG) is showing weak band at 2124 cm-1. According to the reference index, 2124 cm-1 weak band represents alkyne bond. Since there is no alkyne bond in...
30 May 2019 148 3 View
04 May 2019 6,362 3 View
Are there any bioisosteric replacements of triple bond (alkyne) which were employed for lead optimization or scaffold hopping? Thanks.
23 April 2019 2,656 4 View
Several articles report the use of catecholborane as mediator for stereodirected synthesis. Among products are many boron-free compounds. But, when catecholborane is treated with an...
03 April 2019 9,773 2 View
03 April 2019 2,601 5 View
Hello, I would like to know if there is a way to follow the reaction leading to the formation of 1,3,5-triazines using a alkyne and dicyanamide other than NMR? Preferabally using TLC but I can't...
31 December 2018 9,286 5 View
I was working on Husigen reaction with copper 1+ catalyst (cuso4 with sodium ascrobate) for this month. But, the result is not so well. A lot of white ppt formed. I tried to change the order of...
11 December 2018 4,815 1 View
For a study I had to record the 1H NMR of Propargyl bromide in D2O where it is barely soluble. The spectra that I got had the peaks of methylene proton and terminal alkyne proton at d=3.87 (d,...
20 August 2018 6,288 2 View