Actually I'm doing the reaction of bis alkyne with 2 azidopyridine but in this reaction yield is less , can anyone suggest to increase the yield of reaction bcoz in reaction reduction also occurring!
I am working on cervical cancer. I have cervical cancer cell line, but for negative control non cancerous cervical cell line is not available with NCCS, Pune. So can someone provide me C33A cell...
01 April 2024 1,357 2 View
Hello, I want to do a thermal electrochemical simulation of an LGM50 battery. The cathode is NMC811 and the anode is graphite-silicon. How do we add all the properties of the anode is COMSOL...
05 September 2023 7,904 2 View
How to get the values of Reference exchange current density i0,ref (A/m2), which is the exchange current density when Eeq=Eeq, ref for COMSOL modeling of the battery pack?
26 July 2023 3,352 0 View
Do the values given in the COMSOL battery material library enough for battery simulation or every time for anode and cathode we have to enter the equations and values for the Diffusion coefficient...
23 July 2023 7,070 2 View
Hello all, i am trying to model a battery using electrochemical thermal coupled model, and while defining porous electrode, they are using exchange current density values. How to calculate the...
16 May 2023 5,187 1 View
Hello all, i am trying to model a battery using electrochemical thermal coupled model, and while defining porous electrode, they are using exchange current density reference values as shown in...
27 April 2023 5,774 0 View
I wish to highlight the structural domains in the integrin receptors for which I need exact amino acid's location (start and end). Literature has mentioned the different domain names, but not...
14 March 2023 6,556 0 View
Dear All, I am trying to simulate a cylindrical battery pack performance at different ambient temperatures using COMSOL lumped parameter model. I am not having any experimental data of OCV at...
12 March 2023 1,826 1 View
I have the output (-out.cms) file of the protein ligand simulation from Desmond. I wish to analyse some different aspects of the obtained Desmond output file in Gromacs. What are the necessary...
27 February 2023 9,764 0 View
For this, I want to implement a charge-discharge cycling boundary condition which involves 3 steps. Step 1: Charge at a constant current (I_cell) upto a maximum cell cut-off voltage (V_max). Step...
19 February 2023 9,919 5 View
In order to proceed with the quantification of an Azide Alkyne Cycloaddition reaction efficiency by using a fluorogenic probe with Cy5-DBCO, I first need to construct a calibration curve. The...
16 May 2024 6,266 5 View
I am performing azide-alkyne cycloaddition using a propargylated small molecule (alkyne) which is getting incorporated into proteins and biotin azide for pulldown by strepavidin beads. I am seeing...
24 October 2023 535 1 View
I have tried various transition metal catalysts of Zn/Cu/Al/Fe/ as Lewis acids, but no product.
20 June 2023 2,054 1 View
Hello eveyone, I'm trying to conjugate azide-MMAE compound to a protein. The azide-containg group is soluble in DMSO. The problem is when i combine all the ingridients for the reaction i get...
08 June 2023 7,243 1 View
In one of the articles, propane butane mixer is used. It is written that 15% of butane, 84% of propane and 1% of C2 and C5 carbohydrates are used to prepare propane butane. Does anyone have...
20 May 2023 880 0 View
I plan to do a reaction as follows, which requires dehydration condensation with concentrated sulfuric acid. Will the terminal alkyne group be affected? I am a little confused.
24 May 2022 6,382 0 View
Hello, I am setting up some reactions by using standard click chemistry: Azide + Alkyne in DMF/water, Ascorbic acid, Copper (II). I am having problems with the reprudicibility of the reaction....
15 December 2021 7,962 3 View
Hi, everyone! There is a problem about CuAAC efficiency that troubles me a lot. I modified a water soluble comb-like copolymer polyallylamine-graft-PEG (PAA-g-PEG) with azidoacetic acid (about 15...
20 November 2021 8,996 6 View
help me to do the reaction of 2-azidopyridine with alkyne or preparation of 2-azidopyridine
11 November 2021 8,766 2 View
I am trying to do a small scale (approximately 20 micromol of azide and 50 micromol of alkyne) click reaction using CuSO4.5H2O (5-10 mole%) and (+) sodium -L-ascorbate (20 mole%). My alkyne and...
26 September 2021 9,476 4 View