I'm working on the production of microencapsulated lactobacillus reuteri powder using different carriers on a spray dryer. There is a 60-70% decrease in the viable cell count after the spray drying. I have been using whey protein concentrates, gum Arabic, maltodextrins, sodium alginate, trehalose in different concentrations and proportions.
Is there any other method (Except Freeze drying) to develop encapsulated L. reuteri powder where I can store at room temperature.
Thank you.
lower input temperature as much as possible, also you can add sodium alginate and mannitol. mannitol has been shown to increase protein stability in spray drying.
Thank you for your answer!
Do have suggestion regarding the fludizied bed coating of L. Reuteri.
as far as I recall, you can not dry a liquid formulation with fluidized bed dryers. you can only dry a wet solid form like wet granulation.
for drying liquids we have spray drying, freez drying and supercritical fluid drying methods
- Badges
- Science topic
- Similar topics
- Biological Science
- Anatomy
- Tissue