These are microvascular complications of diabetes, but my question is about full detail diagnosis and animal models of microvascular complications including retinopathy, nephropathy and neuropathy be made with easy review and methods. As this is an essential subject and need full information. How plants and polyherbal formulations can be tested.
Maybe the following papers will help you:
1. William T. Cefalu; Animal Models of Type 2 Diabetes: Clinical Presentation and Pathophysiological Relevance to the Human Condition, ILAR Journal, Volume 47, Issue 3, 1 January 2006, Pages 186–198, https://doi.org/10.1093/ilar.47.3.186
2. Robinson R, Barathi VA, Chaurasia SS, Wong TY, Kern TS. Update on animal models of diabetic retinopathy: from molecular approaches to mice and higher mammals. Disease Models & Mechanisms. 2012;5(4):444-456. doi:10.1242/dmm.009597.
3. ANTONIOS CHATZIGEORGIOU, ANTONIOS HALAPAS, KONSTANTINOS KALAFATAKIS and ELLI KAMPER .The Use of Animal Models in the Study of Diabetes Mellitusin vivo 23: 245-258 (2009).
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