Often medicinal plants are first exploited by gathering the plants as they grow wild. This has the advantage of being cheap but can damage a plant populations ecology.
Within one strain of a plant the concentration and composition of the active compounds under investigation will vary. To develop the active compound as a viable commercial product, researchers may be tempted to gather large volumes of the plant. In this way, they can ensure they find the best example of the plant for commercial development...
If people propagating it for commercialization is ok, but they use the plants or plant products, plant parts it causes loss of biodiversity and loss of native plants