Have read some article where it is mentioned Vit D have a protects Multiple Sclerosis.
I wanted to know how actually it acts.
If anyone can share some of the papers of the mechanism it will be great help.
Hi Jit
check this link
https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0086484/
regards
-Vihas
Hello Jit,
for a very exciting perspective see my recent interview with Mr Coimbra from Brasil.
His theory is somewhat different and has been prooven very effective in more than 4000 patients so far!
Best
David
http://www.vitamindwiki.com/Interview+of+Dr.+Coimbra+-+Vitamin+D+protocol+for+Autoimmune+diseases+%E2%80%93+2016
Hello Jit Chatterjee
Some researchers think vitamin D may have potential to prevent MS or reduce the number and severity of relapses.
Vitamin D plays an important role in developing healthy bones, but researchers are also starting to uncover the role of vitamin D in many other areas of health. It’s now known that vitamin D plays a role in the immune and nervous systems, although the mechanism of action is still being studied.
Some cells in the immune and nervous systems have receptors for vitamin D. Receptors are found on the surface of a cell where they receive chemical signals. By attaching themselves to a receptor, these chemical signals direct a cell to do something, for example, to act in a certain way, or to divide or die. The vitamin D receptors on nerve and immune system cells mean that vitamin D is somehow affecting the cell.
When immune system cells are exposed to vitamin D in laboratory experiments, they become less inflamed. This could mean that vitamin D affects the immune system and makes it less likely to attack other cells in the body. Some researchers believe that this means vitamin D has the potential to prevent MS from developing. It could also affect relapsing remitting MS by reducing the number of relapses and how severe they are.
Most people get vitamin D from exposing their bare skin to sunlight. Some research has suggested that children who get lots of sun are less likely to develop MS as adults. So, if one grows up in a place that gets lots of sun, this individual is less likely to develop MS than someone who grows up in a place where there is little sun.
Exposing the skin to sunlight could affect the immune system in other ways apart from producing vitamin D.However, research does show that people with higher vitamin D levels are less likely to develop MS or have a relapse if they already have it.
http://articles.mercola.com/sites/articles/archive/2014/11/17/vitamin-d-deficiency-asthma-multiple-sclerosis.aspx
http://www.mayoclinic.org/diseases-conditions/multiple-sclerosis/expert-answers/vitamin-d-and-ms/faq-20058258
https://www.vitamindcouncil.org/health-conditions/multiple-sclerosis/
http://www.lifeextension.com/protocols/neurological/multiple-sclerosis/page-01
http://www.medscape.com/viewarticle/728504
Dear Jit:
I'm sure you are aware that Vit D 25 is really a secosteroid, hormone, right? And that the measurement of a 25 Vit D level is a biomarker of disease.
You may want to provide your scientific mind with an alternative perspective that does not provide support for it's use in chronic disease: www.mpkb.org
Also this paper: http://mpkb.org/home/publications/albert_autoimmunity_reviews_2009
And this is a list of papers and UTube presentations: http://mpkb.org/home/publications
The use of Benicar/olmesartan is a novel method to provide the chronically ill human body with a "VDR temporary stand-in"(with higher affinity than 1-25 Vit D) so that the activation of the innate immune system happens which reverses chronic inflammatory and auto-immune diseases.
Finally, some unpublished case study research involving 62 patients over 4 years who took Benicar/olmesartan and used an immunostimulatory model to heal: http://np-privatepracticeassoc.com/
If I can be of further assistance, please let me know.
Sincerely,
Trudy J. Rumann Heil MS, ARNP, CLNC
Scottsdale, AZ USA
www.mpkb.org
http://mpkb.org/home/publications/albert_autoimmunity_reviews_2009
http://mpkb.org/home/publications
http://np-privatepracticeassoc.com/
As far as I understood it remains to be clarified whether this represents an immunological effect or is rather a marker of a healthier lifestyle (kind of exercises in the park vs. coach potato smoking watching tv). So we should watch carefully but beware to overrate it yet.
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