Hi Adil,

in theory yes but in practice I guess you'll have some differences. In fact it depends on the power of your chemical to induce tumors, first, and second it depends on how homogeneous are your individuals. It has been described in several papers that animal models from the same strain can derive with time. hundreds of variations are created at each generation. some don't have effects since they occur in non regulating or gene regions, but it's not the case of all. at the exception that your rats are from the same brood, you maybe get some differences.

but still nothing sure, you'll see.

fred

If you treat exact way with exact amount at exact age and gender, probably you will get more or less similar results, tumors size can be slightly different, and time of tumor appearance may slight vary, but certainly, all will show tumors, none will be resistant to tumors.

I think Frederic's answer is more relevant. Theoretically, it might seems possible, but practically it is near not-possible. We must consider the biological/physiological heterogeneity of the cells. Not all the cells in the tissue functions exactly the same, and there are difference on the relation functionality of cells. Additionally, the location of cells in the tissue is also contribute to the level of activity. Upon treatment of the cells would respond similarly and this is true for the tissues too. So, now its the matter of a number of individuals in populations being mutated. So, the expected result could not be homogeneous. Rest is explained earlier.