I am working on a cancer target where multiple mutations are present in the protein retrieved from rcsb pdb. I am getting an error in autodock vina so wish to know the procedure for docking mutated protein.
You can use these videos , very useful for docking using PyRx
https://www.youtube.com/watch?v=gtAur4Rj7Lo&t=16s
https://www.youtube.com/watch?v=niw6gHDLfO4
Many Thanks
You better use Autodock as Vina throws the error for substitutions
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