This is not my subject, but as no-one had answered, I thought I would look to see what I could find here (online in UK):
Dhillon, K. S., Singh, B. B., Kumar, H., Bal, M. S., & Singh, J. (2006). Treatment of vaginal prolapse in cows and buffaloes. Veterinary record, 158(9), 312.
https://www.researchgate.net/publication/7259919
- it might be worth contacting the authors of this who are on ResearchGate?
Dharani, S., Kumar, G. S., Sambasivarao, K., & Moulikrishna, K. (2010). Management of a severe post-partum vagino-cervical prolapse in a graded Murrah buffalo with Renault’s truss and antibiotic therapy. Buffalo Bull, 29(4), 311-314.
From a biomechanical perspective we can say that the uterus is suspended by uterosacral-like ligaments. We also know that 48 hours before labour, the collagen of the cervix and probably the ligaments lose 95% of their strength. Placental relaxin hormone plus other hormones in critical concentrations play a large role. After delivery of the placenta, everything quickly returns to normal. Purely on basic principles, it would seem logical to push the prolapsed uterus back into the vagina immediately after delivery of the placenta.
As regards drug treatment, I cannot see how it would work, as the problem is now mechanical.
If I had such a situation in my cow, I would be very careful about believing claims that drugs or pills would help