Hello Sabah, could you please provide more info on your specific objective? do you want to have KO animals? do you try to produce a protein into a specific organ?

There are several possible reagents you can use, PEI-based or not.

Best, Sandra

Dear Sandra

Thank you for your attention. I want to use PEI for gene delivary in nude mice .

I tumorize the nude mices  and now I want to treat them . For treat i need  suitable transfected reagent for invivo.

what is your suggestion?

Besr Regards, Sabah

You are welcome!

if you want to deliver a plasmid into your mices, the only PEI-based reagent I know is JetPEI from Polyplus. 

We, at Lipocalyx, have also PEI-based reagents but we are specialized for mRNA delivery. It means we can help you to get a very strong protein expression in a context of mRNA-mediated therapy, but not with DNA.

For more info, you can follow the link below.

At your disposal if you have further questions.

Bests, Sandra

https://viromer-transfection.com/in-vivo-delivery