in resource limited settings, the may be need to carry out platelet function test without the use of equipment. which is the best technique and is the result comparable to standard platelet function test using automated techniques?
Functional platelet studies after a period of high interest are currently less frequent because attempts to correlate in-vitro outcomes with the in-vivo platelet function have not been encouraging. So, thromboelastography and aggregometry with ADP, ristocetin and other agents are practically abandoned. The in vivo studies, such as the bleeding time or the vascular fragility test, are burdened by the lack of standardization and, in any case, they are global tests that investigate different phases of the platelet vascular response. Ultimately, only generic automated tests such as total and reticulated platelet counts provide partial information that is not always easily interpretable.
Yes, we did. If you like, we can start communication regarding this issue. If you like, contact me via [email protected]. Best wishes ! Christoph Sucker
interested Christoph Sucker , can we start communication regarding this issue?