I am working on Exosomes that is derived from cells that are engineered to express scFv of Anti-HER2 antibody. I want to see its expression in TEM. Can I directly label the exosomes with the Protein L-GNP or do I need to use Anti-Anti HER2 antibody and secondary antibody then stain with Protein L GNP?
Can anyone suggest literature on Protein L-GNP immuno gold staining in TEM?