Has anyone experineces with a good material to create a dissolvable vasculature template (at hirachical, larger scales)?

Johannes Hackethal @Johannes-Hackethal-2

03 September 2018 0 8K Report

Hi,

I plan to embedd a vasculature template in natural ECM gels (collagen, fibrinogen, gelatin,..), connect it to a peristaltic pump and finally mature the 3D "vascularized object" in a bioreactor. I'm just wondering which materials could work best in terms of solubility/toxicity/cross-reactivity to the ECM gel, as I don't have experience in this specific field so far? PVA, alginate, phosphate based glass, others...?

Thaks a lot for your feedback/energy,

Johannes

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