For hepato or reno-protective effect of plant extract, is it OK to use long evan rat model? Why many prefer to use male rat model for renal disease?

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Hamza Belkhodja

It has been justified due to the variable nature of female data caused by hormonal fluctuations associated with the female reproductive cycle.

Pachava Vengal Rao

Males have higher metabolic rate when compared to female this t is the reason we choose male rats for hepatoprotective studies