whether the Fragmentations of the compound formed was more in GC-MS or LC-MS. Is because of the separation by gaseous carrier used in GC. if so, why not electrospray is not much fragmented?
Gone through nice report. Attached below
http://www.chem.agilent.com/Library/selectionguide/Public/5989-6328EN.pdf
Thank you for sharing your time and provide the refs. regarding this.
The Agilent documentt sent by Ketan Variya give some important explanations at respect. Both methods could be efficient, it depends of the vvork aims and samples characteristics and composition. If you are trying to study a compound degradation and intermediates formation, in my opinion, LC-MS is recomended. The higher temperatures employed on GC-MS could produce more degradation compounds than that ones really present at the sample (artefacts).
Thank you sir, thank you for your kind response to share your opinion and valuable time to my query. Sir, if i suppose to study a volatile compounds like pesticides which one is more efficient and valuable. Suggestions needed. Thank you
Dear Usharani:
If you are going to study volatile compound like pesticides, I think that GC-MS is a better choice, because of reduce time on analysis and results processing and interpretation. The GC-MS spectral database vvith pesticides data are really ussefull.
Respected Dr. Oscar Sir, Thank you very much for sharing your viewpoints and time to my query.
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