You can make fluid domain by "fill" tool in ansys design modeler and other way is that make domain for that specific area and change it solid to fluid.
To create a fluid domain in ANSYS Design Modeler for a compressor or turbine, you need to extract the internal flow region by using the Boolean subtract operation. First, import the solid geometry, then create an enclosure around the fluid region and use the "Boolean → Subtract" function to remove the solid parts, leaving only the flow volume. This method accurately defines the fluid region for CFD analysis, ensuring proper meshing and simulation of airflow, pressure, and heat transfer in the compressor or turbine.