Inbreeding depression occurs when closely related individuals are bred together over multiple generations, leading to a decline in the overall fitness and performance of the offspring. In plant breeding, inbreeding depression is a concern because it can result in reduced vigor, lower yields, increased susceptibility to diseases, and other undesirable traits. To counteract inbreeding depression, breeders often employ techniques like selective outcrossing or hybridization to introduce genetic diversity and restore vigor to the breeding population.