Is a drug always more soluble than its hydrate counterpart?

I am buying some compounds for enzyme inhibtion assay. I want to use neutral compound and not salt form. I don't clearly understand if there is diff in assay with neutral or salt form but for now...

02 March 2016 4,135 4 View

Help with protein inhibition assay setup?

i want to DPP4 protein inhibition assay of at least 10 compound with 96 well plates. Both the standard drug (sitagliptin) and the substrate is present at 100uM conc during assay. I want triplicate...

01 February 2016 1,425 7 View

Can the same micro plate reader used for ELISA testing be used for enzyme inhibition assay that reads colorimetric absorbance?

01 February 2016 6,439 4 View

Pubmed search help?

i need to check if a compound has been tested for a certain protein. Pubmed seems to have such info but there is a ton of things and very confusing i need two straight process 1) A list of all the...

10 November 2015 783 2 View

What is your perception on using visual analysis or quantitative approaches to evaluate data from single-case research designs (n of 1 trials)?

Results of single-case research designs (i.e., n-of-1 trials) are often evaluated by visually inspecting the time-series graph and computing quantitative indices. A question our research team is...

03 March 2021 687 1 View

Is there any expert in Smart PLS who can help me?

Dear colleagues, I have a manuscript that needs an expert in smart PLS to run the analysis, Is there anyone expert and ready to help me, please?

01 March 2021 8,212 3 View

How can I make stacked bar graph with scatter plot?

I want to make a stacked bar graph with showing each data value as dots. I tried with graph pad prism, version 6, but could not succeed. Does anyone have tried before making such graphs?

01 March 2021 9,383 1 View

What could be reason for getting such type of graph for complex impedance in case of polymer blend films?

Its effect appears in real part of ac conductivity also. Can anyone suggest any reason behind it?

26 February 2021 3,487 3 View

Can I use a graph from a another source in a thesis?

I have a permission from X company to use their graph from a report, but they have a reference in the bottom left corner of the graph as follows: "Source: Database Y". Is it OK to use this graph...

24 February 2021 2,269 3 View

I have need of XRD graph analysis software for phase identification. Can you please provide links for software tools which can be downloaded?

i am trying to download x'pert high score software, but can't download it. please do suggest software for phase analysis

24 February 2021 5,687 4 View

Could you please suggest to me research in which a relation between the shear wave velocity and the degree of saturation for stone was discussed?

Hi all, I am looking for a graph or a relation that relates the degree of saturation and the shear wave velocity for the marlstone. Looking forward to your suggestions Best Regards

24 February 2021 9,690 1 View

Can two EC50 values with different hill slopes be compared?

Hello, I fit a classical dose response curve Y=Bottom + (Top-Bottom)/(1+10^((LogEC-X)*HillSlope)) to my data (not related to inhibitors etc). The model I use is purely qualitative but it fits...

23 February 2021 8,155 5 View

Algorithms to filter corrective max and min from a set of data?

I've got this 5 year Direct Normal Irradiance data I downloaded from https://re.jrc.ec.europa.eu/. I ordered this by year and by every 24 hours because I need the DNI curve by max in summer, min...

17 February 2021 2,777 5 View

There is any numerical criterion for identifying neighbours for Voronoi /Gabriel graphs?

If there is a set of n points in a plan (with known x, y coordinates), can I use a numerical criterion to establish if two points are neighbours, given the definition of a neighbour for Voronoi...

17 February 2021 6,914 4 View