Despite the widespread use of B. thuringiensis, only few clinical case reports of illness related to the use of B. thuringiensis have been published:

Gordon, R. E. 1977. Some taxonomic observations on the genus Bacillus, p. 67-82. In J. B. Briggs (ed.), Biological regulations of vectors: the saprophytic and aerobic bacteria and fungi. U.S. Department of Health, Education, and Welfare, Washington, D.C.

Green, M., M. Heumann, R. Sokolow, L. R. Foster, R. Bryant, and M. Skeels. 1990. Public health implications of the microbial pesticide Bacillus thuringiensis: an epidemiological study, Oregon, 1985-86. Am. J. Public Health 80:848-852.

Noble, M. A., P. D. Riben, and G. J. Cook. 1992. Microbial and epidemiological surveillance programme to monitor the health effects of Foray 48B BTK spray. Ministry of Forests, Vancouver, British Columbia, Canada.

Samples, J. R., and H. Buettner. 1983. Ocular infection caused by a biological insecticide. J. Infect. Dis. 148:614\

Warren, R. E., D. Rubenstein, D. J. Ellar, J. M. Kramer, and R. J. Gilbert. 1984. Bacillus thuringiensis var. israelensis: protoxin activation and safety. Lancet i:678-679

Monitoring studies following large-scale B.t. spray programs have shown that exposed people carry B.t. in their tissues. Мore than 11 percent of nasal swab samples taken from patients surveyed by doctors in Vancouver (Canada) following a gypsy moth spray program were found to contain B.t.k. B.t. was also found in cultures taken from patients in Lane Couny, Oregon following a gypsy moth spray program there. Monitoring studies also show that exposed people report a variety of health problems that they believe to be associated with B.t. exposure.

For example, during the Vancouver spray program, almost 250 people reported health problems, mostly allergy-like or flu-like symptoms. During a Washington gypsy moth spray program, over 250 people reported health problems and 6 were treated in emergency rooms for allergy or asthma problems.

http://eap.mcgill.ca/MagRack/JPR/JPR_22.htm

http://onlinelibrary.wiley.com/doi/10.1111/j.1574-695X.1997.tb01026.x/pdf

Thank you so much Alex

Dear Mohammed Fayyadh

Pls. find the attached files

Hoping this will be helpful

Regards

Prof. Houda Kawas

http://www.health.state.mn.us/divs/eh/pesticide/bt.html

http://www.beyondpesticides.org/assets/media/documents/mosquito/documents/BacillusThuringiensisIsraelensisNZ.pdf

http://www.who.int/ipcs/publications/ehc/en/EHC217.PDF

http://stopogm.net/sites/stopogm.net/files/healthrisksbtheinemann.pdf

http://npic.orst.edu/factsheets/BTgen.pdf

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4524/full

https://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+7823

Please see attached article, which is from National Pesticide Information Center (NPIC), USA. The article summarizes good info for Bacillus thuringiensis pesticide. One paragraph it describes as following:

"What are some signs and symptoms from a brief exposure to Bacillus thuringiensis (Bt):

Bt is low in toxicity to people and other mammals. Several studies have found no evidence of sickness or infection as a result of exposure. However, some products with Bt have caused eye and skin irritation. In one study, rats breathed in very high doses of concentrated Bt. Some had runny noses, crusty eyes, and goose bumps. Others were less active or lost weight.

In another study, people were surveyed before and after aerial applications of Bt. Most people were not affected. However, some people with hay fever reported certain symptoms. These included difficulty with sleep and concentration, stomach upset, and nose/throat irritation. Seasonal factors, such as pollen, may have contributed to some of the effects.

Scientists also evaluated whether Bt can cause allergic reactions. Researchers found that farmworkers exposed for one to four months did not experience any problems related to their airways, nose, or skin. However, further exposure showed evidence of an immune response and the potential for skin allergies to develop."