Does the Venous PO2 go higher if the arterial PO2 is made very high?

18 May 2020 1 2K Report

I have been always told that the venous (mixed venous of Central venous) PO2 does not go above 40, even if the arterial PO2 is elevated to very high levels (say 150) by increasing the FiO2 in cases where there is no increased tissue demand

Why would the venous PO2 not rise?

Vijo Poulose

Friends,

I have no definite answer to my own question

But I did a small trial. For my patients in ICU (most were intubated), I increased the FiO2 to 100% and did the ABG as well as a VBG (from the CVP line in the neck)

Let me give you the paired readings of 7 patients (ABG Po2/ CVP Po2)

Pao2 315/ Pvo2 63

349/

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