Sharpe [1] and colleagues used the National Cancer Data Base to study the effect of bilateral mastectomy for early-stage breast cancer on length of hospital stay, readmission rate, 30-day mortality, and time to adjuvant therapy.

The authors begin by acknowledging the recent increase in bilateral mastectomies for patients diagnosed with early-stage breast cancer, a trend that is entirely driven by patients rather than experts. They also point out that surgeons typically address reasons for and possible benefits of different procedures and often leave out the possible (unintended) harm caused by such procedures or options. In this case, it is important for clinicians to figure out whether a delay in the initiation of chemotherapy could result in harm.

Longer wait times may be related to the practice of obtaining additional preoperative imaging with MRI, or consultations with plastic surgery or genetic specialists for second opinions. National guidelines from the National Comprehensive Cancer Network and the National Quality Forum recommend adjuvant chemotherapy to be administered within 120 days of diagnosis of breast cancer.

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Reference: 

1. Sharpe SM et al. Impact of Bilateral Versus Unilateral Mastectomy on Short Term Outcomes and Adjuvant Therapy, 2003-2010: A Report from the National Cancer Data Base. Ann Surg Oncol. 2014 Apr 12. 

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