Does the clinical diagnosis and Time required to perform the procedure essential components of a request for a histologic report of an excisional biopsy
Dear Mohammad, the diagnosis or the differential diagnosis or in some cases the clinical findings give the histopathologist a guide lines for a proper report as well as a proper biopsy sample taken whatever technique followed.
Dear Mohammed, if I understood correctly (the following only as example):
You examine a patient and (hopefully) end up with a "clinical diagnosis". If you cannot be sure about what you see, you will have at least a view of and will establish (a) "differential diagnosis, -es". If you are responsible to chose the method (and ONE of methods may be an excisional biopsy for histological examination - which means usually: fixation, dehydration, embedding in paraffin, sectioning, staining and examination by a (histo-)pathologist, who will write a report....) you - perhaps as internal specialist - will order an excisional biopsy (e.g. performed by a specialized colleague, or - e.g. a surgeon in an other Department will have to do it). If the circumstances are life-threatening, it might be too late to order an excisional biopsy, I guess.... since usually such a routine method lasts at least some hour(s) (up to 24/48 hours - the latter especially if Immunohistochemistry is needed), including a written report. Even if you order a method it will last - depending on the organisational circumstances and distances to the Pathology Labs - at least 1 hour to arrive at a pretty certain diagnosis (and there might be differences regarding the different organ systems .... skin, muscle, vs. suction or needle - FNA - biopsies from certain organs, like kidney, liver etc.). Usually the Clinician/Internal specialist does have at least a certain clue (knowledge) about the methodology (or useable techniques) for taking a representative excisional biopsy for histopathological examination.... but usually (and this has been my experience for long) there will be at least direct and personal consultation with (histo-)pathologist how to do which technique (at least until such biopsies become routine standard by consent or S.O.P.('s) respectively)...And finally: the method used and the skills of the performer(s) / the organisation will define "the time required to perform the procedure".