According to psychological research, permanent anxiety with adrenaline secretion damages DNA and causes abnormalities. Can this be scientifically verifiable?
Stress can cause a slight headache or migraine, this is mainly due to chemicals such as adrenaline and cortisol, which is released from the body during stress, in addition it makes your muscles tense, which leads to more pain.
I believe that empirical studies are providing a lot of light on the biochemical events that are triggered by stress, Its direct relationship with different types of cancer and its interconnection with lifestyle, in particular with the kind of food that has been adopted by citizens.
Without a doubt, DNA, given its structural nature, is a sensitive and perfect target for such events.
Know in advance, through personalized genetic medicine, our genetic predispositions for stress.
know how to choose, in consequence, the type of profession in which we are going to study and that we will practice in our future life, to know if we really have aptitudes to support the levels of stress that, this profession, usually imposes us.
Exercising a profession that we dislike also causes stress and with this, may appear the metabolic disorders that we are now discussing.
There is evidence to indicate that these metabolic disorders are related to cancer.
Receiving an early and effective emotional education, as shown by Dr. Daniel Coleman, helps us to avoid stress and with this we contribute to the prevention of health risks that now occupy us in this important discussion that we are maintaining.
I have searched enzymes for DNA repair in my protein database (please see file; HepG2 fucoidan).
Fetal hepatocyte Hc, and Hepatoma HepG2 has no repair-protein.
However, healed normal HepG2 (cultured with fucoidan) has DNA mismatch repair protein Msh6/G/T mismatch-binding protein at 4.5, DNA mismatch repair protein Mlh3 at 6.9, DNA polymerase theta at 2.5, and DNA polymerase kappa at 10.4 μg/mg cell protein, respectively.
LC tissue (with leprosy) has DNA polymerase epsilon, catalytic subunit at 4.1 μg/mg tissue protein.
HCC tissue (named as No.6) has DNA polymerase epsilon, catalytic subunit at 3.9 μg/mg tissue protein and DNA-repair protein complementing XP-G cells (response to UV or response to ONNV) at 24.2 μg/mg tissue protein.
Serum of 4mo boy (before biotin therapy) has DNA polymerase delta catalytic subunit at 1.8 μg/mg serum protein and serum of the same boy (after 3mo of biotin therapy; alopecia has been cured but he is in vitamin K deficiency) has DNA cross-link repair 1A protein at 8.2 μg/mg serum protein.
Serum of 1y11mo (girl, with anorexia, with excess biotin) has DNA ligase 3 at 2.0 μg/mg serum protein and DNA polymerase kappa at 11.4 μg/mg serum protein.
Therefore, stress may upregulate DNA repair system, but it is not directly linked to the cancer.
Stresses seem to activate the DNA-repair system, and the lysogenized or hidden virus may be re-induced. Then, this induction of co-infected viruses (HCV and HIV-1 in the case of HCC) causes the cancer. Fucoidan stops of the multiplication of these +ssRNA Flavivirus and +ssRNA Retrovirus possibly by effectively inhibiting Reverse Transcriptase (RT) and less degree to inhibiting RNA dependent RNA polymerase (RdRP). Fucoidan (the product of Noto-peninsula Japan and not the product of Okinawa Japan) surey reduced HIV-1 for 19.8-fold and HCV for 4.1-fold in three-days treatment at 0.102 mg/mL.
Stress can release mediators that affect physiology and psychology of the one under stress, it can induce oxidative stress that can lead to DNA damage.