In TRB's National Cooperative Highway Research Program (NCHRP) Report 572: Roundabouts in the United States, you'll find a Summary of operational models (Table 3) in which the number of lane is specified for each method. The link is:
http://nacto.org/docs/usdg/nchrprpt572.pdf
Also, in TRB's National Cooperative Highway Research Program (NCHRP) Report 673: Roundabouts: An Informational Guide (Second Edition), you'll find the HCM method to assess capacity and Level of Service. The link is:
http://nacto.org/docs/usdg/nchrprpt672.pdf
Regarding your first question, I agree with William Guzman about the use of Vissim given that this software allows to simulate right and left hand drive conditions without a notorious difference.
Hope you'll find this information useful for your research.