Dear colleagues,

My rather basic question from the looks of it:

I have a short amino acid sequence of the cell-penetrating peptide such as TAT (GRKKRRQRRRPQ). If I would reverse it to get QPRRRQRRKKRG, would I expect it to behave in the same manner or not? Should I regard this as a new peptide with potentially different functionality?

Thank you,

Best wishes,

Vito

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