Does heparin stimulate elastin biosynthesis in adult vascular smooth muscle cells?

22 April 2015 1 2K Report

What are the other ways to induce elastogenesis in a tissue engineered vascular construct? Does surface patterning play any role in this regard?

Tarun Agarwal

Kindly Check out this paper for your answers:

"Modulation of elastin expression by heparin is dependent on the growth condition of vascular smooth muscle cells: up-regulation of elastin expression by heparin in the proliferating cells is mediated by the inhibition of protein kinase C activity."

Regards,

Tarun

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