Does euthanasia by CO2 inhalation cause NF-kB activation in mouse heart or body in general?

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I am considering injecting cisplatin directly into an equine sarcoid tumour that is chronically refractive?

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Malcolm Nobre

Hello Tushar

You can refer to the link below:

Article Carbon dioxide inhalation causes pulmonary inflammation

Regards.

Giovanni Colonna

I wouldn't call it euthanasia because CO2 is toxic and kills by acidification of the blood and lung inflammation. Euthanasia should not interfere with the animal's metabolism or be painful.