Does anyone understand the classification of KIR gene haplotypes based on the presence or absence of these genes?

31 October 2024 0 8K Report

Help me define my KIR haplotype.

I am starting to genotype KIR genes in a population. I'm unsure how to classify the haplotypes using standard PCR. Here’s an example of genes found in one person: 2DL1 2DL2 2DL4 2DL5 2DS2 2DS3 2DS4 3DL1 3DL2 3DL3

This profile seems to fit haplotype B. However, it also appears to have elements of haplotype A. Am I wrong? Is there a possibility that this sample could belong to haplotype AB? Does this type of haplotype exist? If anyone knows of any documents or tables that could assist in classifying the haplotypes, could you please share them?

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