Guassian QST3 output has 1 imaginary frequency but I don't think it is the correct TS. What should I do?

I ran a QST3 calculation under an expanded basis set: S 0 6-311+G(2df,p) **** H C N O 0 6-311+G(d,p) **** (this is the same expanded basis set I used for optimizations) When the calculation...

09 March 2017 6,038 3 View

Has anyone used an ELISA for porcine Calprotectin?

25 August 2016 4,721 1 View

Isolating dendritic cells from the murine colon?

I'm currently working on isolation of dendritic cells from the murine colon, but haven't been able to get too much. I'm currently using EDTA washes followed by a collagenase/DNAse digestion, then...

29 May 2016 3,772 5 View

Does anyone know any recent articles that discuss artificially intelligent machines that aid in medical diagnoses?

Anything regarding the ethical implications too would be great.

15 April 2015 7,166 9 View

How to perform EEG classification of Alzheimer and control groups?

I am doing a project on classification of EEG signals of Alzheimer's disease and control groups. Previously, I extracted the alpha power of the EEG signals and found out the strengths. I want a...

18 February 2021 8,502 2 View

Does anyone have a stack of images of action potentials or abnormal brain scans?

I need a stack of black and white .jpeg/.tiff/.jpg/.png images across time of either action potentials, neurons firing, or brain scans (comparing disease and normal brain, disease progression,...

09 February 2021 2,648 3 View

Patients with chronic kidney disease could get COVID-19 vaccine?

04 February 2021 278 4 View

How can you accurately induce calcium overload and measure membrane potential in cultured Tg2576 neuronal cells using whole cell patch clamp method?

Hi there, I'm currently working on a project where i need to design an experiment but as i have little to no experience with this level of experimental design and no face to face help i am really...

22 January 2021 6,728 3 View

Where can I get a Music therapy database for Alzheimer's Disease?

I am working on the effect of music therapy on persons with Alzheimer's Disease. I require EEG signals of healthy individuals and people with Alzheimer's Disease/Dementia that have undergone music...

22 January 2021 8,613 5 View

What is the best nanoparticles that can be easily prepared & can be used in silencing the BACE1 gene for prevention of Alzheimer disease?

I want to do a research about the nanotechnology and management of Alzheimer. I found a lot of ideas about nanoparticles that already studied in that field but I do not know which of them is the...

20 January 2021 1,052 3 View

What is role of chronopharmacology or circadian rhythms in metabolic diseases including obesity, diabetes and cardiovascular diseases?

Chronopharmacology is branch of biological science which deals with daily life, sleep and wake, day and night, feeding and fasting and other effects. we can manage many diseases including...

18 January 2021 9,045 3 View

Is there no general protocol for vaccination study?

Hi, I searched vaccination study to know which MLD50 is suitable for influenza virus study in pubmed. But why every vaccination and challenge conditions are different? Is there no guideline or...

16 January 2021 7,984 3 View

Does use of hand sanitizer negatively impact the skin microbiome?

Hello, Most hand sanitizers contain 60-80% alcohol. Alcohol destroys organisms including bacteria, fungi, protists, and enveloped viruses by breaking down the plasma membrane. In recent...

16 January 2021 6,923 11 View

How do we interpret sf12 PCS and MCS scores?

I always read "the higher the score the better the health", however, it seems to me that it is not true by the way the two summary measures are constructed. Or maybe - highly plausible - I am...

11 January 2021 4,620 1 View