letrozole extraction from Blood Plasma for LCMS analysis. Can some one share or suggest a protocol and the options i have.
Thank You
Have you checked the manuscript by Beer et al., Anal Bioanal Chem (2010) 398:1791-1800? It describes the development and validation of a LC-MS/MS method to analyze tamoxifen, anastrozole, and letrozole in plasma. It looks pretty straight forward.
Good luck!
Thank You Daniela Hampel
It was Very helpful article
Smile Regards
It will depend on your method sensitivity! Start with protein precipitation.
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