For anti-caries, oral antimicrobial agents and oral health care products development, I am looking for an in vitro mouth model system for experiments. One of my mentors (Dr. Bennett T Amaechi, UTHSCSA) has one, but I am looking for somthing more advanced or a commercial one.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918665/figure/F2/
Article Anti-cariogenic effect of a cetylpyridinium chloride-contain...
this is a review paper about this topic
Artificial mouth model systems and their contribution to caries research: a review.
http://www.ncbi.nlm.nih.gov/pubmed/12726700
Hi Karthikeyan,
From the sound of it, the Constant Depth Film Fermenter (CDFF) fits the bill. It facilitate control of a number of environmental parameters and can mimic the oral cavity very well. It can allow for the growth of biofilms associated with particular oral diseases through the control of the gaseous environment and change or addition of nutrients. In particular, the model allows for a variety of substrata, including hydroxyapatite or enamel.
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