Is it possible to run an optimization program (in MATLAB) whose objective function is the output of circuit simulation (in PSPICE----Orcad Capture).
I am not sure, but may be the following book covers such scenario:
http://www.amazon.com/MATLAB-PSpice-Electronic-Circuits-Yang/dp/8972839973
http://www.mathworks.co.uk/matlabcentral/fileexchange/40988-matlab-and-pspice-for-electronic-circuits
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