Does anyone have any references or literature about fatigue mechanisms which cytokines are involved in it in none-disease subjects? Does anyone have any references about impact of cytokine on exercise/physical activity-induced fatigue or other immune system components and mechanisms which leads to fatigue delay during exercise/physical activity?
Hi Mahmoud
Have a look at this review article which is written by Josef Finsterer. It may give you some clues.
- Biomarkers of peripheral muscle fatigue during exercise-
I hope it helps.
Good luck
Gleeson, M.; Bishop, N.C.; Stensel, D.J.; Lindley, M.R.; Mastana, S.S.; Nimmo, M.A. The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease. Nat Rev Immunol, 11, 607-615.
Dear Marzieh and Ali
Thanks for your comment and for sharing your knowledge and attached paper about my asked question. It's great.
Dear Kim
Thank you for your mentioned reference, it's great, but I think it is indirect issue about my focus which is about fatigue delay during exercise/physical activity. However one of the causes of muscle and CNS fatigue may be inflammation that exercise reduce it by anti-inflammatory effects, I think.
Mr. Delphan
see this recent study about the T helper cytokines
http://www.ncbi.nlm.nih.gov/pubmed/24673178
In adiction, a paper from PlosOne showed a desbalance between Th17 and Regulatory T Cells.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793976/pdf/pone.0074722.pdf
Hello,
The following reference might be of interest for you:
Psychoneuroendocrinology, 2012, 37(5), 671-684.
Best regards & Merry Christmas !
Andrea
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