Hello

We want to test invitro, if the B-cell therapeutic antibodies can help reduce the production of antibodies by B cell into the culture. I have a general idea for the experimental set up like treating the PBMCs with different concentrations of the antibodies with and without stimulation and culturing them for 7-10 days.

I was wondering if anybody has done such experiment before and can share a protocol?

Thank you

Saroja