Milena Miljkovic (miljkovic.milena57@) yahoo.com)
The following publications can be helpful to find out more information about bile acid transporters:
Thank you very much, professor Milena M Miljkovic .
The role of bile acid transporter of ASBT in intestine was identified and I am wondering what is the role of ASBT in cholangiocyte or gallbladder epithelial cell.
Milena Miljkovic ([email protected]).
Brief information about the role of ASBT in cholangiocyte or gallbladder epithelial cell, can be found at the following link:
https://www.solvobiotech.com/transporters/asbt-transporter
OATP-type transporters are also capable of transporting bile acids. The below is an article in 2012 that summuarizes the contribution of genetic polymorphisms that lead to jaundice and hyperbilirubinemia syndromes. The introduction of OATP inhibitors are also known to increase plasma concentrations of various bile acids.
van de Steeg, E., Stránecký, V., Hartmannová, H., Nosková, L., Hřebíček, M., Wagenaar, E., … Schinkel, A. H. (2012). Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver. The Journal of clinical investigation, 122(2), 519–528. doi:10.1172/JCI59526
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