Can I use g_MMPBSA with Cas9?

Hello, I'm trying to see the interaction between the Sa Cas9 protein and the guide RNA. I ran a molecular dynamic simulation on it and then estimated the energy binding using the g_MMPBSA...

17 December 2020 661 2 View

What is the Method of Moment theory and what differentiates it from the MLFMM solver?

Hi everyone, It's been quite a time since I have started searching the web for clear explanations on the Method of Moment (MoM) theory for electromagnetic field computing. Does anyone know a...

23 September 2020 2,763 4 View

What are the latest research in control system ?

Hello all, I want to do my research in control systems (nonlinear, robust, adaptive) and I'm wondering what to study ? Do you guys have any ideas ? I am a bit lost as those fields are...

06 February 2020 8,659 15 View

How to make multivariate time series regression in R?

I m analysing the determinant of economic growth by using time series data. Collected data covers the period from 1980 to 2017. There is one dependent variable and 12 independent variables. The...

06 January 2020 8,411 14 View

Can the bending of a light ray passing the sun correctly be explained by gravitoelectromagnetism?

04 October 2019 9,860 9 View

How to Conduct SPSS Reliability Test For Multi-variable Questionnaire?

Greetings, I am a DBA student conducting a study about "Factors Influencing the Adoption of Payment Cards in Lebanon". My research model, theoretically based on the Technology Adoption Model...

29 January 2019 2,369 7 View

Issues with diagram in AMOS, can anyone help ?

Hello, I'm a student and for my last essay, I have to use structural equation modeling. I'm kind of lost here, and I don't really know what i'm doing on the software, and I have poor statistical...

14 August 2018 8,002 3 View

Has anybody an experience of Fluid exchange interaction into Abaqus CAE Finite Element Package ?

Hello everyone, I am investigating Pressure evolution in response to external solicitation in Finite Element Analysis. I try to iterate my model by enabling a Fluid Exchange interaction between...

14 November 2017 6,973 5 View

How to compute the ionization energy within a frozen solvent cage in PCM

Hi, I'm trying to calculate the IE of a molecule (solute) within a solvent. It seems like I can get a fair approximation using PCM solvation model, however I do not want to let the environment...

30 July 2017 8,247 3 View

Where does this information come from?

from uniprot : Nedd4 binds, in vitro, through the WW2 and WW3 domains, to neural isoforms of ENAH that contain the PPSY motif.

25 July 2017 9,694 1 View

Can I run spearman's correlation on non monotonic data? Is it advisable?

Hi all, I am running a partial correlation analysis on mood data. I want to see if there is a correlation between scores on a novel hypomanic mood scale and existing measures of hypomania - the...

25 February 2021 1,619 3 View

How to handle studies which report perfect effect sizes in a meta-analysis using Pearson's r?

I'm in the process of updating a meta-analysis and in one of the new studies, effect sizes are reported as Tau-U. Two of the effect sizes are reported as Tau-U = 1.00. I am using Andy Field's...

24 February 2021 2,265 3 View

Interpretation of Goodman - Kruskal Gamma squared?

Dear colleages, Eta squared is dominantly used in reflecting the explaining power the same manner as a squared partial correlation coefficient (R2p ) from multiple linear regression: as the...

22 February 2021 7,801 3 View

Can I arbitrarily take a cycle number of 40 for the gene that was not expressed at all in qPCR results calculation?

I ran RT-qPCR for a control and a treated group and it appears that my gene of interest was not expressed at all in any of the subjects in the control group. So I was wondering if I could...

20 February 2021 6,243 10 View

Does anyone know if the Quantstudio 3 qPCR machine requires a passive reference when Using SYBR? I ran a qPCR and got the plot in the attached file.?

I know that my target is in my sample as I extracted it from cell culture myself. These plots show some amplification. The first one seems O.K for the first 36 cycles but then collapses at the...

14 February 2021 2,809 2 View

How do I group questions of SPSS under one variable for Spearman's r?

12 February 2021 5,379 5 View

Are there any exception like work hardening in metals elastic limit due to dynamic loading?

The samples made out of spring steel are taken from same lot. The specimens were shaped following heating to forging temperature - Forming- Hardening -Tempering methods. After storage of almost 6...

11 February 2021 952 6 View

What effect size should i use for a meta-analysis when study data violate normality assumptions?

I'm looking for advice regarding what effect size to use for meta-analysis. Our question is whether the number of individuals in a group affects the per-capita productivity of that group. Does...

10 February 2021 5,510 8 View

Having trouble with qPCR amplification plots. My curve's never seem to reach a plateau. Any ideas?

The parameters of the curve all seem acceptable, typically reactions results are above 0.9852, -3.1 to -3.6 slope, and 90-110% reaction efficiency. The results seem to be what I would expect from...

04 February 2021 1,138 3 View

Queries regarding the rain flow counting algorithm?

02 February 2021 9,790 2 View