I am currently writing my dissertation on the use of non-invasive ventilation to deliver nitric oxide in neonates and I was wondering:
- What are people‘s experiences of using non-invasive iNO with CPAP, Nasal cannula, oxygen hood etc?
- Which gestational have you primarily used it with?
- What were the indications/ underlying pathologies?
- Have you found this has reduced the need for mechanical ventilation or ECMO?
- Have you needed to deliver higher doses to achieve the same effect seen on mechanical ventilation?
- Which countries have you seen this being practiced?
Any other insights or information would be greatly appreciated.
Nitric Oxide usage with non-invasive ventilation will result in inaccurate dose delivery of the drug. For best dosing and best drug delivery, nitric oxide should be used with endotracheal intubated patients
It is important area ,waiting for the results
The gestation age who will need this technique will be FT with MAS and PPHN s well as preterm who develop BPD and PPHN
I have used inhaled nitric oxide with non-invasive ventilation in a few infants with severe BPD- I must say, they did not stay extubated for long. Infants w BPD and concomitant pulmonary hypertension are probably served better by placed on sildenafil to manage their pulmonary hypertension and this has been our practice with our pulmonary colleagues.
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