Do Gödel incompleteness and Turing’s halting problem set internal limits only to mathematical reasoning or to the larger program of scientific discovery? Ironically, it was Gödel, a logician who demonstrated the incompleteness of mathematics. Then why does logic (sans mathematical symbolism) lack the predictive power of mathematics? What does mathematical symbolism bring to the table that logic alone is lacking? And if there is a limit to the effectiveness of mathematics is this limit ontic, epistemic or both? Have we run up against those limits in contemporary science?