off course

Thank you for replying.

I find it interesting that much focus is placed on the microbes role in fermenting carbohydrates, but not much is said about the other fuels they can obtain from the host's diet.

Best regards,

José

http://www.nature.com/nature/journal/v489/n7415/abs/nature11552.html

Dear all, 

I just realised most fat would be digested before it reaches the colon. My reasoning and a quick literature check would be that gut microbes would be better equipped for protein and carb metabolism.

Cheers,

José

Maybe the following papers will help you:

1. Peter Schönfeld, and Lech Wojtczak. Short- and medium-chain fatty acids in energy metabolism: the cellular perspective. Journal of Lipid Research Volume 57, 2016,943-954.

2. Krajmalnik-Brown R, Ilhan Z-E, Kang D-W, DiBaise JK. Effects of Gut Microbes on Nutrient Absorption and Energy Regulation. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. 2012;27(2):201-214. doi:10.1177/0884533611436116.

3. Morrison DJ, Preston T. Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism. Gut Microbes. 2016;7(3):189-200. doi:10.1080/19490976.2015.1134082.

4. Alcock J and Lin HC. Fatty acids from diet and microbiota regulate energy metabolism [version 1; referees: 2 approved]. F1000Research 2015, 4(F1000 Faculty Rev):738 (doi: 10.12688/f1000research.6078.1)

5. Lu, Y. et al. Short Chain Fatty Acids Prevent High-fat-diet-induced Obesity in Mice by Regulating G Protein-coupled Receptors and Gut Microbiota. Sci. Rep. 6, 37589; doi: 10.1038/srep37589 (2016).

Please go through the following RG links and PDF attachments.

Article Gut microbiota confers host resistance to obesity by metabol...

Article Impact of Dietary Lipids on Colonic Function and Microbiota:...

Article The Role of Short-Chain Fatty Acids in the Interplay between...