When scientists discover an unknown DNA structure and sequence, how do they confirm that the proposed structure is correct by comparison with known DNA sequences? Additionally, how is the nomenclature of such sequences standardized in scientific practice? Finally, in the context of extinct animals, how do researchers determine and verify that these species existed during specific geological periods based on DNA and fossil evidence? When an ancient DNA is extracted from fossils how do scientists determine the evolutionary relationship between extinct species and present organisms?
Go for blastn first of all. You will get the similarity percentage with already existing sequences. To determine the evolutionary relationship between extinct species and present organisms, you must have DNA from both available with you and then using specific set of primers you can check the polymorphism and by making dendrogram after all the primer data similarity and dissimilarity can be assessed.
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- Biological Science
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