I wanna disperse modified silica Aerosil 300 (with MPTMS).
If I use probe sonication (100w power for 20min), Is it possible the breakdown of silica nanoparticles and degradation of surface alkyl chain (due to modification by MPTMS) ?
In what solvent you want to disperse the particles? If the particles are dried it will be vary hard to redisperse them in water even at high sonication power. I do not think you can break the particles and the only concern with the surface group has to do with a potential temperature increase due to sonication.