This is a really interesting question! Unfortunately, I'm not equipped to answer it! So I'll just offer a few hardly relevant comments....
The financial and economic crises of that period, shook the confidence of ordinary citizens in deep and profound ways. The consequences still do, and will continue to do so, probably for the rest of my life-- I'm in my early 60s. It made people in the developed world significantly poorer. It drained their confidence in the future, in authority, in many different types of institutions, in banks, in hospitals, in government and on and on....
They could afford to donate less to medical and other research--those figures should be available. Less to research more generally. And, I think, they probably did, and do, trust less. Hence problems now with Oxfam and medicine sans frontiere and the sexual behaviour of their onsite workers. It was an economic disaster bigger than the Great Depression, and still has a long way to run.