xNPs and diseases
Hey all, I am about to do a research the requires investigating a SNP in the promoter of the bradykinin 1 receptor B1R (G-699 to C) substitution. The paper I found uses SSCP and [32P] - alpha...
06 July 2019 5,611 1 View
Usualy the restriction fragment length polymorphisms technique is referred to by PCR-RFLP which means you should do a PCR reaction first. Is there any non-PCR based RFLP technique?
07 August 2016 8,675 3 View
Is it wrong to use TBE buffer when running genomic DNA? and why?What are the main differences between those two buffers?
07 August 2016 9,925 3 View
I have reverse sequences (AB1 format), can I base on reverse DNA sequences to perform nucleotide alignment, convert nucleotides to amino acids and deposit the sequence in GenBank database?
11 August 2024 5,138 1 View
I received an e-mail invitation to join the editorial board of Clinical Cardiology Updates. While I have published a few articles related to cardiovascular disease, there are lots of colleagues...
06 August 2024 8,981 8 View
I want to introduce a point mutation (change in one nucleotide) into my gene of interest (DNA binding domain) I have designed primers as recommended on the Data sheet of the kit : -Both primers...
05 August 2024 9,059 3 View
I have a theoretical framework for preparing a interview guide to assess the unmet care needs of a sub population of chronically ill patients and their caregivers(dyadic interviews).
04 August 2024 8,798 7 View
I am conducting my research regarding blood coagulation in patients with CKD. I observed a reduction in post hemodialysis aPTT and PT values compared to pre hemodialysis values. But most of...
30 July 2024 3,467 0 View
I am currently conducting a mendelian randomization study, and I was attempting to use PhenoScanner to look for potential confounders associated with the selected SNPs (any SNPs significantly...
23 July 2024 5,703 0 View
Only Probiotics Related
22 July 2024 6,454 0 View
Hello! everyone, I am trying to study in silico Protein-Protein and Protein-RNA interactions. Now, is there any tool with which I can identify the interacting amino acid residues or the...
14 July 2024 950 2 View
I was performing a site directed mutagenesis of a plasmid, the goal was to change/insert 4 nucleotides into the original plasmid using primers as seen in the image: Now I now there may be some...
04 July 2024 5,221 2 View
What are the latest, modern and effective treatments for treating thalassemia and sickle cell anemia? If you find new research, please send it to me
28 June 2024 7,297 3 View
